The NBC comedy-drama's final episode, 'Chuck vs. the Goodbye', will air on January 27.
"I predict very few dry eyes," Schwartz told TVLine. "Mine did [well up]. It was really emotional."
The executive producer went on to say that the finale, written by Chris Fedak, provides a "really, really great" resolution for long-time viewers.
"I think that every Chuck fan is going to be very satisfied," he said.
Angus Macfadyen recently signed up for a villain role in the final season of Chuck, while Cheryl Ladd will play the mother of Sarah (Yvonne Strahovski) and Bo Derek will also make a cameo appearance.
The series airs on Fridays at 8/7c on NBC.
> Chuck exec 'scared about series finale'
Watch a behind-the-scenes look at the final season of Chuck below: