Fans are invited to attend the Profiles in History public sale on December 15 and December 16 at the Paley Centre for Media in Beverly Hills, where they have a chance to bid on famous props from the popular sitcom in the 'Icons of Hollywood Auction'.
Among the items for sale is the Central Perk cafe's orange couch, which Jennifer Aniston and her Friends co-stars congregated on each week from season four.
The couch is expected to fetch $4,000 - $6,000 (£2,552 - £3,828), while the accompanying green chair is estimated at $3,000 - $5,000 (£1,914 - £3,190).
Watch an amateur tour of the Central Perks set, featuring the orange couch and the green chair, below:
The broken yellow frame which decorated the peephole on Monica's (Courteney Cox) door will also go under the hammer and is predicted to take in $1,500 - $2,000 (£957 - £1,276).
Two of Central Perk's coffee cups, Monica's pickle jar, a pair of Friends exclusive Nike Shoes, and prints from various characters' bedrooms will be up for auction as well.
Friends became one of the most popular American sitcoms of the last 20 years during its 10-season run and launched the careers of Aniston, Cox, Matthew Perry, Lisa Kudrow, Matt LeBlanc and David Schwimmer.
Aniston has described Friends as her greatest job, while Schwimmer said that he is incredibly grateful to have landed the role of Ross Geller.
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Watch Friends' opening credits below: