The drama, which airs in the US on ABC Family, stars Alexandra Chando as a young girl called Emma who discovers that she has an identical twin sister.
While Emma is a foster child, her sister Sutton has been adopted and brought up with an apparently ideal lifestyle.
Emma agrees to impersonate Sutton while she pursues a lead on their birth mother, but when Sutton goes missing Emma has to decide whether or not to reveal her true identity.
Charisma Carpenter and Heroes actor Adrian Pasdar are among the other stars who appear in the show.
5* also confirmed that it has picked up the rights to classic series Gilmore Girls, which focuses on the relationship between mother and daughter Lorelai (Lauren Graham) and Rory (Alexis Bledel).
The show is expected to air on 5* during the daytime.
Channel 5's head of acquisitions Paul Fagan said: "With its mix of drama, intrigue and scandal, The Lying Game fits perfectly with 5*'s ethos. Along with the acquisition of Gilmore Girls we are extremely pleased that we can add both these shows to 5*'s strong lineup for 2012."
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