McIntyre took over the lead role in the Starz series after Andy Whitfield left the show to be treated for non-Hodgkin lymphoma. Whitfield passed away in September at the age of 39.
When McIntyre was asked by Collider to talk about Spartacus's journey of vengeance while being responsible for the livelihood of others, he said: "For me, that is this season. They're almost in a different world. They've moved out of the pressure cooker ludus into this unknown.
"Nobody wants to be a slave, but at least they know what that means. They're in the wilds and suddenly they need food and they need shelter, and they need to not be killed by the Romans. There are a whole lot of questions."
McIntyre added: "So many of the players, like Crixus (Manu Bennett) and Agron (Daniel Feuerriegel) and Mira (Katrina Law), and the new characters that we introduce, have opinions on how to approach that. It gets so big because now they're against the Republic, and not just against that segment. Their vengeance is not just one side, and Spartacus has to learn how to be a leader.
"In Season 1, he lost his wife and was put into slavery, and it was about balancing the scales. That still drives him, but he now has a responsibility to so many people. It's where he starts to own and understand what that means.
"So, his journey is a very difficult one because, even a person who may be a natural born leader learns that it's not an easy mantle to take up. He has a very difficult journey, in becoming the leader of these disparate people through Italy to try to take on Rome. It's a difficult path that he's chosen."
Spartacus: Vengeance will premiere on January 27 on Starz.
Watch the opening scene from Spartacus: Vengeance below: