The project, which has been written by Chuck and NYPD Blue scribe Nicholas Wootton, focuses on the life of a police officer as he rises up the ranks to Police Commissioner.
McBride has now signed up to play the lead's partner Owen, TV Line reports.
Owen, who works as a detective, is said to be grumpy and cynical.
McBride has previously had roles in shows such as Human Target and Pushing Daisies and recently had guest spots in How I Met Your Mother and Suits.
Golden Boy is being executive produced by Greg Berlanti, whose previous credits include Dawson's Creek, Everwood, Dirty Sexy Money, Eli Stone and Brothers & Sisters.
Berlanti is also working on another CBS pilot, a comedy starring JoAnna Garcia, and has projects in the works at The CW and USA.