The project - from CSI's Josh Berman and Drop Dead Diva's Rob Wright - will focus on surgeon Grace Delvin (Spiro).
In order to save her debt-ridden brother, Delvin is forced to work after hours as a 'mob doctor' for criminals, according to Deadline.
Spiro recently appeared in the sixth season of Dexter and also featured on Harry's Law, as well as playing the lead in TBS sitcom My Boys.
Necessary Roughness star Jaime Lee Kirchner will also appear in Berman and Wright's untitled pilot. The actress will play a surgical resident who works alongside Delvin and also happens to be the daughter of the hospital board's chairman.
Kirchner previously starred in NBC medical drama Mercy and has also appeared on CSI and Dollhouse.
Justified's Michael Dinner will direct the medical pilot and will also executive produce alongside Berman and Wright.
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