The drama, which has been penned by Goodfellas writer Nicholas Pileggi, is based on the true story of the clash between Las Vegas sheriff Ralph Lamb and Chicago mob fixer Johnny Savino.
Moss has now signed up to play assistant district attorney Katherine O'Connell in the project, Deadline reports.
Katherine is the daughter of a local rancher who grew up as a neighbour to the Lambs.
Moss is possibly best known for her role as Trinity in The Matrix, but she has also had roles in television shows such as Models Inc. and Chuck.
Dennis Quaid has already signed up to play Lamb in the CBS drama, while The Shield's Michael Chiklis has joined the cast as Savino. The project will also star The O.C.'s Taylor Handley as Lamb's son.