The drama is based on a Judith Krantz novel, and tells the story of a successful clothing designer named Billy Winthrop, to be played by Forlani.
Deadline reports that Jessica McNamee and Boris Kodjoe will also feature in the pilot. McNamee will play Billy's friend, a celebrity journalist. Kodjoe will play the attorney of Billy's late husband.
This will be Forlani's fourth foray as a television series regular. She has previously appeared in NCIS: Los Angeles, CSI: New York, and Camelot, where she starred as Queen Igraine.
Kodjoe recently finished filming another ABC pilot, Georgetown, about a group of young people working in Washington, DC. The actor also starred in the spy series Undercovers alongside Gugu Mbatha-Raw, but the show was axed last year.
Scruples is produced by Tony Krantz and Natalie Portman. It is to be directed by Michael Sucsy, who helmed the hit romance The Vow.
Watch Boris Kodjoe in Undercovers below: