The former Total Request Live presenter will head up the new series, which will include Kelly Clarkson, Jennifer Nettles, Lionel Richie and Robin Thicke as coaches.
Duets sees the four artists searching America for their protégés, before choosing two singers to perform duets with them each week on the show.
The finale will have only one artist and their protégé left standing, with the amateur singer signing a recording contract with Hollywood Records.
"This show is going to take the singing competition genre to the next level and I'm absolutely honoured to be a part of it," Quddus said in a statement.
The Canadian MTV VJ also previously hosted Dance on Sunset on Nickelodeon in 2008, and has appeared as an Access Hollywood correspondent.
Kelly Clarkson has previously said of Duets: "The simple fact that I get to go out and find two people that I believe in, sing with them every week, and help them accomplish their dream is an amazing thing that I can't wait to be a part of!"
Duets will premiere on ABC in the US this summer.
Watch the promo for Duets below: