The Republican politician will appear on Tuesday, April 3, reports The Wrap.
"I see this as a good opportunity to bring an independent, common-sense conservative perspective to NBC," Palin told Breitbart News. "We're 'going rogue' and infiltrating some turf for a day."
Former CBS Evening News anchor Katie Couric will also be a guest host on Today's competitor Good Morning America next week.
Palin was the subject of the HBO movie Game Change, which focused on the politician, portrayed by Julianne Moore, during her 2008 vice-presidential campaign.
Palin said that she was not worried about the "false" narrative in Game Change "when there are so many other things to be concerned about".
Watch the trailer for Game Change below: