Monday Mornings - which was originally titled Chelsea General - will broadcast a run of 10 episodes in summer 2013.
The drama is based on producer and CNN chief medical correspondent Dr Sanjay Gupta's book of the same name.
The Ally McBeal creator began working on the project last year, which follows five surgeons who come to terms with mistakes and issues at their hospital's weekly morbidity and mortality conference.
"Monday Mornings is a superb drama brought to life with passion by a gifted ensemble cast and some of the best creative minds working in television today," TNT president Michael Wright said.
Ving Rhames (Pulp Fiction), Alfred Molina (Spider-Man 2), Jamie Bamber (Battlestar Galactica), Jennifer Finnigan (Better With You), Bill Irwin (CSI: Crime Scene Investigation), Keong Sim (Glee), Sarayu Rao (Lions for Lambs) and Emily Swallow (Southland) are among the cast.