The former Dancing with the Stars contestant filmed his scenes as a celebrity judge in a Battle of the Bands in Toronto on Thursday (June 29), reports People.
Bono said that he is a major fan of Degrassi, particularly because lead character Adam Torres (Jordan Todosey) is a transgender teen.
"I work with a transgender teen support group that is part of the organisation Transforming Family so when the opportunity to be part of a series that features a trans teen came up, I was thrilled," Bono commented.
He added that he strongly identified with Adam's struggle to gain acceptance among his peers as a female-to-male transgender.
Bono explained: "Adam's storyline on Degrassi is important to me because it means more transgender representation in the pop culture and it also sends the message to trans teens that they are not alone in their struggles."
His Degrassi episode airs later this year.
Degrassi, which has won two Teen Choice Awards, premieres its new season on July 16 on TeenNick.
Watch a Degrassi trailer below (US only):