According to TVLine, the Soup host will appear on the FX biker drama as a con man who double-crosses the wrong person.
McHale will reportedly be working closely with star Katey Sagal, who recently tweeted a photo of herself and the actor.
She wrote: "Working with a handsome stranger. Yeow! Lucky girl. Love my job."
Season five of Sons of Anarchy, starring Charlie Hunnam and Ron Perlman, debuts in September.
McHale was at Comic-Con earlier this week, where he promoted the upcoming season of Community.