The two HBO series will premiere their second seasons in January 2013, as revealed at the cable network's TCA panel on Wednesday (August 1).
Girls stars Lena Dunham, Allison Williams, Zosia Mamet and Jemima Kirke as four girls in their twenties living in New York City.
The series recently received five Emmy nominations, including a nod in the 'Outstanding Comedy Series' category where it will compete with two other HBO series, Curb Your Enthusiasm and Veep.
Enlightened stars Laura Dern as a female executive who is determined to live an enlightened life after a meltdown.
Earlier this year, Dern won the Golden Globe Award for 'Best Actress - Television Series Musical or Comedy' for her role in Enlightened.
Watch a clip from Girls below: