Produced by The Bernie Mac Show creator Warren Hutcherson, the programme will be called What Would Dylan Do, and will star Rowland in the title role.
According to Shadow & Act, the comedy will focus on a struggling relationship blogger from LA who considers rekindling a romance with her ex-fiancé.
Grey's Anatomy star Brandon Scott and The Game actress Gabrielle Dennis have also signed on in supporting roles.
A pilot episode will begin filming soon, though the show itself has yet to be officially picked up by BET.
Rowland, who has acted in several shows including VH1's Single Ladies, has said that she and her Destiny's Child bandmates are "enjoying friendship".