The singer-actress will revive her role as Buster and GOB's vertigo-addled former lover Lucille Austero in the upcoming fourth season, reports TV Guide.
Minnelli's Lucille Austero appeared in the first two seasons of Arrested Development from 2003 to 2005, often appearing at odds with Buster and GOB's mother Lucille Bluth (Jessica Walter).
Arrested Development's fourth season will see the returns of several of the show's most popular guest stars.
Judy Greer will once again play George Bluth (Jeffrey Tambor)'s mistress Kitty Sanchez, while Henry Winkler and Scott Baio will be back as the Bluths' attorneys.
Mad Men star John Slattery is joining the cast as well.
The fourth season of Arrested Development is to stream on Netflix in the US and the UK in 2013.
Watch Liza Minnelli in a clip from Arrested Development below: