House of Lies will debut on Tuesday, October 2 at 10pm, while the latest run of Edie Falco's Nurse Jackie will launch on Tuesday, October 9 at 10.35pm.
Based on Martin Kihn's hit book, House of Lies stars Don Cheadle, Kristen Bell, Dawn Olivieri, Ben Schwartz and Donis Leonard Jr.
It centres on the character Marty Kaan, a cutthroat consultant who will use any means to get his own way.
Meanwhile, the fourth season of dark comedy Nurse Jackie features special guest stars including Rosie Perez, Aida Turturro, Joel Grey, the New York Knicks' Carmelo Anthony and Green Day's Billie Joe Armstrong.
The latest season will feature Jackie (Falco) confronting her addictions and dealing with a new ambitious hospital administrator, played by Emmy Award winner Bobby Cannavale.