The legendary comedian will tape the new comedy special An Evening with Jerry Lewis - Live From Las Vegas on November 18 at the Orleans Hotel & Casino, reports The AP.
Lewis's new television special will see him mix music with comedy as well as reflect on his eight-decade career.
An Evening with Jerry Lewis - Live from Las Vegas is airing on PBS in March 2013 to mark the comic's 87th birthday.
Lewis has battled health concerns in the past few years, most recently being hospitalised in New York City in June for low blood sugar.
He was ultimately released from a medical treatment after being observed by doctors for two days.
Watch Jerry Lewis in the trailer for The King of Comedy below: