The new take on Bram Stoker's classic vampire tale will star The Tudors actor Jonathan Rhys Meyers as the title character.
Knauf - whose credits also include Spartacus: Blood and Sand - will serve as showrunner and head writer, working alongside series creator Cole Haddon, Deadline reports.
The new Dracula will see the Count arrive in Victorian London, posing as an American entrepreneur and planning to wreak havoc. However, his plans are derailed when he encounters a woman who appears identical to his dead wife.
In July, NBC boss Robert Greenblatt promised that the series would be a "new version of the classic Bram Stoker" story.
"In the world of Twilight and True Blood and all the contemporised stories, we thought we'd go back to the original," he explained.
The ten-part drama is being produced for both US network NBC and the UK's Sky Living.
> Casting Dracula: Friday Fiver
Picture gallery - Dracula at the movies: