The pay channel has announced that the follow-up to the 2011 miniseries will be based on J Randy Taraborrelli's book After Camelot: A Personal History of the Kennedy Family 1968 to the Present.
REELZ president Stan E Hubbard said in a statement that his network is happy to present the continuing story of America's most famous political family.
"With The Kennedys miniseries we saw tremendous response to powerful storytelling along with an intense interest in this remarkable family. In his book, J Randy Taraborrelli tells the incredible true story of the Kennedys from 1968 to today," Hubbard commented.
He continued: "The Kennedy family is truly a part of the fabric of America and we're thrilled to once again work with our partners at [Canada's] Muse Entertainment Enterprises to bring our viewers this fascinating and continuing story."
Critics gave 2001's eight-part The Kennedys a lukewarm reception, but Barry Pepper did earn a Primetime Emmy for 'Outstanding Lead Actor in a Miniseries or a Movie'.
Pepper played Robert F Kennedy in the original miniseries, with Katie Holmes playing Jacqueline Kennedy and Greg Kinnear portraying John F Kennedy.
Watch a trailer for The Kennedys below: