CBS is holding its annual telethon on Wednesday (December 19) to help raise awareness for childhood adoptions.
Matchbox Twenty and Melissa Etheridge are also slated to perform on A Home for the Holidays.
The X Factor USA's Rachel Crow will also share her personal story, having been adopted out of poverty when she was just a baby.
Crow's family will also receive a special award during the telecast.
This year's A Home for the Holidays is being organised by the Dave Thomas Foundation for Adoption and the Children's Action Network.
CBS airs A Home for the Holidays on Wednesday at 8/7c.
Watch Rascal Flatts' 'I'll Be Home for Christmas' music video below: