The long-running soap opera will now run through to September 2014 for the time being, NBC entertainment president Jennifer Salke confirmed.
"We are thrilled to announce that Days of our Lives is not going anywhere," she said. "It is NBC's longest-running drama series by far and is one of the most historic brands in television.
"We commend Ken Corday and the entire creative team on continuing to keep the stories and characters fresh, exciting and relevant year after year."
Sony Pictures Television president Steve Mosko added: "Days of our Lives has maintained a loyal and dedicated fan base for more than four decades and continues to reach a new generation of viewers.
"We appreciate NBC's support over the years and, as the show celebrates this significant milestone, we are thrilled that the show will continue to be a part of the NBC family."
Days of our Lives will reach its 12,000th episode on January 11.
The series began as a half-hour drama in 1965, before it increased to an hour the following decade.
Fellow soaps All My Children and One Life to Live are currently being developed for online revivals following their cancellations on TV.