The singer / actress is developing the project at NBC, according to The Hollywood Reporter.
The pilot episode is based on a pitch from Nick and Robin Bakay. Writer and actor Nick Bakay penned the recent Kevin James movies Paul Blart: Mall Cop and Zookeeper, but is also known for voicing Salem the cat on Sabrina, the Teenage Witch.
"We are thrilled to team up with the multi-talented Jessica Simpson to bring this new sitcom to life on NBC," said Ben Silverman, founder and chairman of production company Electus.
Silverman went on to describe Simpson as a "modern-day" Lucille Ball with "incredible comedic chops".
"From running a fashion empire to wrangling her public image as a new mum, we see Jessica's character approach a variety of 'everyday' circumstances that will get audiences laughing out loud," he promised.
Simpson herself said: "I often find myself thinking that no-one could ever make up the things that actually happen in my life - so between the real-life elements and a great team of writers, I think we'll have people laughing!"
The Dukes of Hazzard actress previously developed a comedy pilot at ABC in 2004; Jessica saw Simpson play a popstar-turned-news anchor, but the project was not picked up to series.
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