My Sister's Keeper coincides with the release of the Destiny's Child singer's upcoming gospel album.
The Entertainment One Television show will follow Williams and her sisters as her new solo album is released.
"We're very excited to expand upon our relationship with Michelle on this new collaboration that will provide fans with a peek into her everyday life," said executive producer Tara Long.
Michelle Williams added: "Working together on my new gospel album and television series, I am excited to share with everyone a behind-the-scenes look at the inspiration and journey of recording for the album, performing, fun family times and other unforgettable experiences out together with my dear sisters."
Her currently untitled fourth studio album will be her third gospel LP, and is expected to be released some time in 2013.
Williams recently joined her Destiny's Child bandmates Beyoncé and Kelly Rowland for the former's Super Bowl halftime show for a medley of hits.
She described the reunion on February 3 at the New Orleans Mercedes-Benz Superdome as "a blast".