The show's executive producer Tim Kring previously suggested that a feature or miniseries could be made to tie up the storylines on the programme, which was cancelled by NBC earlier this year.
However, the network recently announced that it has decided not to pursue the project.
Quinto, who played Sylar, told Entertainment Weekly: "It's disappointing that there was such a lack of resolution. But unfortunately that's just the nature of network television... Nothing really surprises me in terms of network and studio bureaucracy. It's the way it goes.
"If it was in their best interest I'm sure they would have done it. And for whatever reason, they didn't think it was. So that's a bummer. But we just have to accept it and move on."
Quinto added that he loved working on the show and explained that he is pleased that his co-stars are finding new projects.
"I have nothing but fond memories and fondness for the people who gave me that opportunity," he said. "I miss everybody, but I'm also glad to know that everybody is moving forward with as much momentum as possible."