The 48-year-old has appeared in a guest star capacity on episodes of ER and The Sopranos. She is also known for her three-year stint as secretary Gwen Taylor on LA Law.
The actress is to portray the recurring role of Kendall on the popular ABC series, Entertainment Weekly reports.
The character was described by the show's producers Carlton Cuse and Damon Lindelof as being "an intellectual beauty with a sharp edge to her wit who is caught committing corporate espionage and has to lie her way out".
Cuse recently used clues on a Twitter message to announce that actor William Atherton has been cast on the programme.