The actor, who starred in over 200 episodes of the original Beverly Hills, 90210 from 1990 until 2000, told WENN that he is open to the possibility of returning in the future.
"They approached me with a couple of opportunities and there was nothing that made sense for Brandon to be there. I thought it made more sense for me to come as a director...[But], I learned long ago never to say never."
Priestley, who also served as a director and executive producer on the original drama, recently helmed an episode of 90210 called 'Off The Rails'.
Other former stars to have returned for the spinoff include his on-screen sister Shannon Doherty (Brenda Walsh), Tori Spelling (Donna Martin) and Jennie Garth (Kelly Taylor).