The band will appear in an episode of the CW drama in February, Entertainment Weekly says.
The instalment will see the characters going to a music festival in the desert.
Train are expected to perform their latest single 'Drive By' when they turn up on the show.
Other musicians who have previously had guest appearances on 90210 include Billy Ray Cyrus, Brandy and American Idol's Kelli Pickler.
90210 returns with a new episode in the US on January 17. The show airs in the UK on Tuesdays at 9pm on E4.
Listen to Train's 'Drive By' below: