The UK popstar will perform two songs on the CW show in an episode slated to air in April, according to Entertainment Weekly.
The 28-year-old will help Liam (Matt Lanter) and Navid (Michael Steger) in their efforts to impress a pro-surfer, and will sing his tracks 'Troublemaker' and 'Right Place Right Time'.
Ne-Yo, Billy Ray Cyrus and Taio Cruz are among the music acts to have previously appeared on the teen drama series.
90210 returns to the CW with new episodes on January 21 at 9pm ET.
Murs released his debut US album Right Place Right Time in December, which differed from his third UK release of the same name and included his first US single 'Heart Skips A Beat', featuring Chiddy Bang.
"I am so excited that I am getting the chance to release my music here in the US," Murs said at the time.
"'Heart Skips A Beat' has been a big hit for me around the world, but I never thought I'd be able to bring it to the US!"
Watch the video for Olly Murs's 'Heart Skips A Beat' featuring Chiddy Bang below: