Bridesmaids and Crazy, Stupid, Love have each received multiples nominations in the movie categories, with Midnight in Paris and Horrible Bosses also receiving nods.
Jennifer Aniston, Melissa McCarthy, Jason Bateman and Steve Carell have all been recognised for their performances in top comedy films from the past year.
30 Rock heads the television nominees, with nods for 'Comedy Series' and for the show's stars Alec Baldwin and Tina Fey.
Modern Family, Curb Your Enthusiasm, Parks and Recreation and Saturday Night Live have also been nominated.
Recipients of this year's 'Johnny Carson Award', 'Comedy Icon Award', 'The Comedy Awards Digital' and 'Best Viral Original' will be announced in the next several weeks.
The second annual Comedy Awards will be taped at New York City's Hammerstein Ballroom on April 28, 2012.
The awards show will then air on Comedy Central on May 6 at 9/8c.
> The Comedy Awards 2012: Nominations in full
Watch a special look at last year's Comedy Awards below (US only):