The 49-year-old actor, author and comedian will play Dr Gordon Wyatt, an FBI psychiatrist who must assess whether Special Agent Seeley Booth, played by David Boreanaz, is fit to return to work.
Fry is also to star as troubled country solicitor Peter Kingdom in new ITV drama series Kingdom later this year.
The episodes of Bones featuring Fry will be broadcast on Sky One on March 29, April 5 and April 26.
