Abrams told Give Me My Remote that "you can't please" every single fan, but that he is personally satisfied with the show's conclusion.
"[Showrunner] Joel Wyman, this season - knowing it was the last year - did an unbelievable job at not only wrapping up the story but also ending the series on its terms, in a really emotional, unexpected, intense, cool way," he said.
"I've been involved in shows that have had resolutions that have been in some cases adored; in other cases, [they ended up] enraging fans and in some cases, [it's been] a split. There is no one way to end a story - you can't please everyone."
However, Abrams insisted that the two-part Fringe finale is "satisfying" and does not feel "in any way tacked on".
"It feels inevitable - it's a really emotional ending... and surprising as well," he promised.
John Noble - who plays Walter Bishop on Fringe - recently claimed that the show's last episodes could be "one of the great finales of all time".
The last two episodes will be simulcast on Fox in the US and on Sky1 in the UK.
> Fringe recap: September returns in 'The Boy Must Live'
Watch a promo for the Fringe finale below: