Producer Aaron Kaplan told reporters at the TCA press tour that the new series will be both "offensive" and "sweet" like the original series.
"Like anything else, it's a challenge and that's one of the things that... MTV loved about the original as well," Kaplan said. "In spite of how offensive it could be, it was incredibly sweet.
"We made up a lot of original words that we can get past standards. And... the fact is when you take these four boys and put them in dating situations and situations that involve being irresponsible, you'll find that they can be just as offensive as any kid across the world."
Showrunner Brad Copeland added that the themes of The Inbetweeners are "universal" and not limited to UK teens, IGN reports.
"The idea of kids in high school struggling to have sex and drink... they're universal," he argued. "They've been around since [1982 film] Porky's at least. And I think it's always the same thing, whether it's that or American Pie or Breakfast Club.
"It's just people tapping into their own experiences, and what you're going to see is all of us tapping into our own experiences."
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The first season of the US Inbetweeners is comprised of twelve instalments, with half of those being described as "skewed versions" of UK episodes.
"We have plots that we really enjoyed from the series that we wanted to put in, but usually we had to tweak it a little bit just because to fit... the American sensibility," Copeland explained.
"And I think the six episodes that we did on our own this season worked really, really well. It definitely gave us a launchpad to now transition into our own story and to take these universal themes and to take the characters from the original British version and make it our own, our own place, somewhat like The Office did."
The Inbetweeners debuts on MTV on Monday, August 20.
Watch a clip from MTV's Inbetweeners remake below: