Romero - the director of classic zombie films Night of the Living Dead and Dawn of the Dead - told io9 that he had been offered the chance to helm multiple episodes.
"I didn't want to be part of it," he said. "Producers called and said, 'Do you want to direct some of these?' and I said no. Because I just didn't think it was me."
Romero also admitted that he has not seen any of The Walking Dead.
"I love the [comic] books, [but] I never watched any of the episodes because… my zombies are sort of my own," he said. "I've been waiting to see the whole first season, which I missed because I've been travelling. I've been waiting to look at it, but I haven't seen any of it."
The Walking Dead's former showrunner Frank Darabont previously revealed that the series was influenced by Romero's work.
"We're throwing back to the good old days," he claimed last August. "We're in a drooling, lumbering George Romero mindset."
The Walking Dead returns to FX in the UK this Friday at 10pm, and continues on Sundays at 9/8c on AMC in the US.
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Watch a trailer for The Walking Dead season two below: