The actor told The Washington Post that his character Rick may be forced to lead his fellow survivors away from Hershel's (Scott Wilson) farm.
"Something happens and they realise very quickly that the farm is not as secure as they may think," he explained.
Lincoln also discussed the "pivotal" secret message that Jenner (Noah Emmerich) whispered to his character in the show's first season finale, suggesting that it may not have been good news.
"This is a scientist who seemingly held all the cards to what this epidemic is about," said the British star. "You would imagine he would have something of value to say on that matter. Well, he chose to kill himself [instead]."
The Walking Dead creator Robert Kirkman recently teased that things will "keep getting worse" for the show's characters.
"There are more dangerous things out there than the zombies," he said. "Things just keep getting worse from here."
The Walking Dead continues on Sundays at 9/8c on AMC. In the UK, the show airs on Fridays at 10pm on FX.
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Watch a promo for the next episode of The Walking Dead below: