Broadcast reports that the show, which was first ordered by Syfy in October, will be set in Boston.
Meanwhile, executive producer Rob Pursey revealed that although the show will keep the original's "chemistry", the characters will be changed slightly.
Pursey explained that the werewolf George will be renamed Josh, while the vampire Mitchell will be Jewish.
"Without letting go of the DNA of the original, it is evolving into quite a different show," he said. "It will be pacier and the characters' hinterlands are broader. So with Josh you get to see another aspect of how he copes with being the outsider."
Pursey added: "Syfy is very keen to take the humour and humanity rather than just the vampires. They want it to push the channel more mainstream."
The script is being penned by Everwood and Privileged writer Anna Fricke and Supernatural scribe Jeremy Carver. The show, which is currently being cast, is expected to go into pre-production next month and is scheduled to air in 2011.
The second season of the UK Being Human will premiere in the US on July 24 on BBC America.