Esposito revealed that the new episodes, which begin next month, will be set directly after the fourth season finale.
"I do know this. Season five takes up right where we left off," he told The Wrap. "Literally, right after Gus's death.
"[Creator] Vince Gilligan does that, I would think, because he wants to be in real time. This is where we left off, this is where we're going to start."
The show's fourth season premiere also picked up directly after the previous finale.
Esposito, whose character Gus was killed in the season four finale 'Face Off', hinted that he could return to the show.
"If I were in [Gilligan's] position, I would more than likely explain some back-history of Gus."
A new promo released from the season shows Walt (Bryan Cranston) in a terse confrontation with his lawyer Gus (Bob Odenkirk).
Aaron Paul recently hinted that the upcoming season will be "very violent" and the show's "dirtiest" yet.
Breaking Bad returns to AMC on July 15. Watch a promo for the new season below: