The American Pie star will appear in a February episode of the CBS legal drama, according to TVLine.
He will play a lawyer who refuses to release the name of a client. Facing a lawsuit of his own, the character will become a client of Lockhart Gardener.
Biggs is best known for playing Jim Levenstein in the American Pie film series and will reprise the role in next year's American Reunion.
He previously starred in CBS sitcom Mad Love but the show was axed after just one season.
His additional TV credits include guest roles on Frasier, Will & Grace and a voice role in the new Teenage Mutant Ninja Turtles.
Dexter star Jennifer Carpenter recently filmed a guest stint on The Good Wife, while Amy Sedaris will play a nemesis of Eli Gold (Alan Cumming) on the show.
The Good Wife returns to CBS this Sunday at 9/8c, following a two-week break.
> The Good Wife is a new show, says CBS exec
Watch a promo for the next episode of The Good Wife below: