The show's former star has criticised the series for what he sees as a dip in quality since Ashton Kutcher took over the lead role earlier this year.
"I'm extremely disappointed with how they're handling what I left behind," Sheen told TMZ.
Despite feeling let down by the show's current season, Sheen offered advice for Kutcher in light of recent claims about the actor's marriage to Demi Moore.
"He's doing the best he can," Sheen suggested. "I don't think the role is cursed."
Two and a Half Men returned for its ninth season on CBS last month, but has faced a steady decline in ratings since its premiere, which brought in almost 28m viewers in the US.