The writer told TV Guide that New Girl's season two story arc sees Jess dealing with being laid off from her job.
"It does feel like a tough moment in her life, but a fun thing to write because the character unhinges," Meriwether teased. "As you see in the second episode, she's off the grid. She gets to explore these parts of herself that she hadn't explored."
She added: "It's been a fun thing to write for the first batch of episodes because you get to see corners of her personality that you haven't seen before."
Meriwether went on to suggest that the second season sees Jess on a "a voyage of self-discovery".
"She's figuring out who she is without her job in the first part of the season; if that changes who she is or if it doesn't," the writer explained. "Also, if she still wants to teach. She has to defend that to herself."
Meriwether further commented: "She met the guys last year and they became friends. This year, you're starting the season and they're already friends. She's learned a lot from them already.
"So, there are parts of the guys in her this season, which are really fun. She has a toughness I think that she grew into last season. But this season starts with a toughness, which is great."
Deschanel said last week that she is proud that New Girl has become a hit because Jess is a character she "hoped other people would" love.
New Girl airs on Fox.
Watch a promo photoshoot for New Girl season two below: