The ABC series, starring Emily VanCamp, will premiere on the channel later in 2012.
Revenge follows Emily Thorne (VanCamp), a young woman who is intent on getting even with those who wronged her and her father, who was framed for a crime he didn't commit.
Golden Globe-nominated Madeleine Stowe (We Were Soldiers) also appears in the show, while the pilot episode is directed by Phillip Noyce (Salt).
"This primetime soap is a delicious guilty pleasure encompassing all the money, power and privilege of the Hamptons and a young woman set on revenge," said Channel 4's head of acquisitions Gill Hay. "It's a compelling watch, which I think E4 viewers will find addictive."
Dayna Donaldson of Disney UK & Ireland added :"Revenge is one of the buzziest, juiciest series around at the moment - ABC Studios have produced a winning combination of intrigue, darkness, and sheer glamour, which is universally entertaining. We're confident that E4 viewers will quickly be hooked."
Revenge will make its UK debut on E4 later this year. In the US, the series premiered on ABC in September, where it is the second highest rated new drama on US television.
> Revenge exec teases 'major' death, 'big' finale, season two
Watch ABC's promo for Revenge below: