The actor plays US Marine platoon sergeant and former al-Qaeda captive Nicholas Brody in the Showtime series based on the Israeli show Hatufim (Abduction).
> Homeland: 'The Weekend' review - The best episode so far?
"I hate this word but I can't think of anything else to say," Lewis told the Evening Standard.
"You know you've hit the Zeitgeist when the piece of entertainment you're a part of has made the political pages of something like the New York Times. It's had that crossover.
"The piece was talking about the withdrawal of troops, and about the way in which [president Barack] Obama has had to finish a s**tty job started by the Bush administration."
He continued: "It said that he actually wasn't doing it that well - but even so, he was doing it.
"And it talked about the paranoia that still exists in our foreign policy, and at home in the US - and that this was comparable to what we were seeing in Homeland."
Lewis was last month invited to attend a State Dinner at the White House to mark the visit of Prime Minister David Cameron and later quipped that he spoke to the president to get a "heads-up on any foreign policy moves" for the show.
Homeland continues on Channel 4 on Sundays at 9pm in the UK. Season two premieres in the US this September.
> Read our recent interview with Damian Lewis
Watch the trailer for Homeland below: