The drama is created and written by Heroes mastermind Tim Kring, and will join the schedule in spring 2012.
Sutherland will play widower and single father Martin Bohm, who struggles to connect with his mute 11-year-old son Jake. Martin later discovers that Jake has a genius gift of noticing patterns that connect random events.
Danny Glover will appear as a professor who also possesses a special gift connected with numbers in a similar vein to Jake.
The pilot episode was directed and executive produced by Water for Elephants' Francis Lawrence.
The series will see Kiefer Sutherland return to television drama following the end of Fox series 24 in 2010.
Fox's President of Entertainment Kevin Reilly said in a statement: "Touch is another ambitious series from Tim Kring that is beautifully executed and has incredibly resonant themes for our times.
"With Kiefer back on the network as the face and force behind this creative new series, I'm confident it will resonate with viewers this spring."
Sutherland added: "Every once in a while, you encounter a piece of material that you just cannot say no to. That, combined with the opportunity to work again with Peter Chernin and the Fox studio and network, makes me thrilled to be a part of this project.
"I also look forward to working with an extraordinary writer and producer like Tim Kring."
Kiefer Sutherland revealed earlier this year that a movie version of 24 will be released in 2012.
> Fox exec: 'Touch is really compelling'