The supernatural drama is based on a series of books by Gabriella Pierce.
It focuses on a young couple who move into one of the oldest apartment buildings in New York City, only to start facing a number of spooky experiences.
Annable has now signed up to play the husband, TV Line reports.
He previously starred as Justin in Brothers & Sisters and has also appeared in shows like Reunion and Third Watch.
News of Annable's casting comes shortly after Lost star Terry O'Quinn signed up to play the owner of the haunted building.
Other projects currently in the works at ABC include soap Devious Maids, a submarine drama from the creator of The Shield, and fairytale show Beauty and the Beast.