Liu can soon be seen as Joan Watson on the new CBS drama Elementary, a contemporary version of Sir Arthur Conan Doyle's Sherlock Holmes stories also starring Jonny Lee Miller as Holmes.
The gender-swapping of Watson has been criticised by some, but Liu told the Wall Street Journal that the change is "a good thing" as it's a reflection of today.
"If you look at the percentage of ethnicities and the percentage of women on television now, it's such a different time," she explained. "That's how you keep things current. You update and you change them accordingly.
"People probably thought the same thing about the president of the United States - how is it possible that you have someone who's not Caucasian? - in that vision. I think things are shifting quite a bit."
Liu added that it feels good to be representing and breaking down the walls for Asian-American actors.
She said: "It's nice to be able to portray an Asian-American on camera without having an accent, or without having to be spoofy. And I think that's a big step forward, because there are still representations of people that are more comedic. And that's not what I'm playing.
"I'm just playing somebody who represents anyone else who would be living in America or outside of it, who is just a regular person."
Back in April, John Cho praised the increase of Asian-American actors on television and commercials.
Cho was recently promoted as a series regular on Matthew Perry's NBC programme Go On.
Other prominent Asian-Americans starring on television include Brittany Ishibashi on Political Animals, Aziz Ansari on Parks and Recreation, Steve Byrne on Sullivan and Son and Mindy Kaling on the upcoming The Mindy Project.
Elementary will premiere on Thursday, September 27 at 10pm ET on CBS.
Watch a promo for Elementary below: