The actor told Zap2it that his take on superhero Oliver Queen/Green Arrow will be more grounded than most comic book adaptations.
"Nobody in our universe has super powers, so that's a big jumping off point," he explained. "I think we find Oliver Queen more injured than we saw him before."
Amell also sought to distance his performance from that of Justin Hartley, who played Green Arrow on The CW's Smallville between 2006 and 2011.
"Other than in name, there are virtually no similarities between [his version and mine]," he claimed. "It's not to say that one's better than the other, it's just that they're so different, it's almost weird to compare them."
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Hartley - who will next be seen in The CW's Emily Owens, MD - previously insisted that he has not offered Amell any advice on how to tackle his Arrow role.
"[Stephen] doesn't need any tips from me," he claimed. "I wouldn't even begin to do that… He's going to be great."
Arrow will debut on The CW this fall, paired with Supernatural on Wednesday nights.
Watch a teaser for Arrow below: