The actor joined the cast of the show as Patrick Logan this season.
According to The Mirror, he has now admitted that he felt honoured to be on the series.
He explained: "As a kid I went down that way for the Universal Studios tour not knowing that as an adult man I would actually be filming with some of the biggest TV stars in America, and also not knowing that I would be on Desperate Housewives which is ranked as one of the top three shows in the history of television around the world. So that was kind of a humbling moment when I walked down that street for the first time to film. It was good."
Barrowman also said that he had fun on the programme, saying: "I really enjoyed it. It's going to air in June here [in the UK]. That's why my hair is so dark at the moment because they gave me what I call Bad Guy, Black Hair. I'm not a very nice guy in it."
Desperate Housewives continues Sundays at 9/8c on ABC in the US and Wednesdays at 10pm on Channel 4 in the UK.