The actor appeared on Access Hollywood on Monday (May 14) to reflect on his eight seasons as Hatcher's on-screen love interest.
"It's been the best thing. I worked with Teri almost exclusively and I learned a ton from her. She's really brilliant comedically, very underrated I think," Denton commented.
He further explained: "We'll have a scene on paper that you're kind of going, 'How is this going to work?' and sure enough, she makes it work.
"And she has a great quality where people pull for her on-screen and I benefited from that because they wanted Mike [Delfino] to be her knight in shining armour because they wanted her to be happy. Teri was a big, big bonus for me for eight years."
Denton was also questioned on Hatcher's relationship with her female co-stars after rumours emerged that Eva Longoria, Marcia Cross and Felicity Huffman excluded her from a gift given to the Desperate Housewives crew.
"I can honestly say I don't know. It could be as simple as they couldn't get together on it, but Teri did do her own gift as well, so if she did get left out, she made up for it," Denton said. "I can honestly say I don't have any idea what the backstory is on the gift."
Desperate Housewives ended its eight-year run on Sunday, with 11.1 million viewers tuning in for the series finale.
Watch James Denton discuss the Desperate Housewives finale below: