Carter Bays, Craig Thomas and HIMYM executive producer Chris Harris will collaborate on The Goodwin Games, according to TV Line.
The project, which sparked interest from several networks before landing at Fox, will follow three estranged siblings who reconnect following their father's death.
Bays and Thomas have also written for American Dad! and The Late Show with David Letterman.
The seventh season of How I Met Your Mother premiered last week on CBS. The sitcom has already been picked up for an eighth run, while Bays has also refused to rule out the possibility of a ninth year.
Other comedy projects currently in development at Fox include Tyler Labine's Guidance, a family sitcom from Scrubs creator Bill Lawrence and a dark comedy from Seinfeld writer Peter Mehlman.
A new project starring Arrested Development's Portia de Rossi and Shawn Levy's Gorilla Time are also in the works.
> How I Met Your Mother exec teases character return