Viewers will learn who womanising Barney (Neil Patrick Harris) is due to marry in the CBS sitcom's season finale.
"It's not another 'tune in next year' moment," Smulders told The Insider. "There's a cliffhanger, but with a big reveal in the finale too."
The Avengers actress added: "Of course there will be division among fans because they want Barney to end up with a few different people, but I hope the majority of them are happy with who he ends up with - I know I am."
Smulders also admitted that she is hoping to see Robin "finally settle down" in the show's eighth run.
"Committing to somebody is a huge step for her," said the star. "She tried with Kevin (Kal Penn) earlier this year and it didn't work out.
"But our creators have actually thought about everything and that relationship was very much needed in order to get Robin to where she's headed."
How I Met Your Mother airs Mondays at 8/7c on CBS.